Structure-activity relationships in the antiinflammatory steroids: a pattern-recognition approach
نویسندگان
چکیده
منابع مشابه
Structure-activity relationships in the antiinflammatory steroids: a pattern-recognition approach.
A pattern-recognition technique has been used to determine structure-activity relationships for antiinflammatory steroids. Experimental results using the human vasoconstrictor test of McKenzie and Stoughton and the rat granuloma cotton pellet method of Meier were correlated with the various substructural descriptors. Steroids were classified into two categories according to potency, and a patte...
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ژورنال
عنوان ژورنال: Journal of Medicinal Chemistry
سال: 1983
ISSN: 0022-2623,1520-4804
DOI: 10.1021/jm00357a003